![]() Metabolic and electrolyte imbalances such as ↓ sodium bicarbonate, ↓ sodium and calcium, ↑ glucose and bilirubin.Nausea, vomiting, constipation, abdominal pain.Oral anticoagulants may have an increased anticoagulant effect.Hormonal contraceptives can decrease the effectiveness of acetaminophen.Barbiturates, carbamazepine, isoniazid, rifampin, alcohol use, and more can increase the risk of hepatotoxicity.Activated charcoal and cholestyramine decrease the absorption of acetaminophen. ![]() Elderly, pregnant or breastfeeding patients, and children under age 2. Patients with renal or hepatic impairment. Precautions and contraindications: Hypersensitivity to acetaminophen. Indications for use: Mild to moderate pain such as muscle aches, back pain, headache, arthritis, sinus pain, toothaches, and menstrual cramps. It is thought that acetaminophen inhibits prostaglandin synthesis in the CNS which results in pain relief and fever reduction. Therapeutic class: Analgesic, antipyretic Pharmacologic class: Synthetic non-opioid It does not have any anti-inflammatory properties.īrand names: Tylenol, Abenol (CAN), Acephen, Altenol, Aminofen, Apra, Atasol (CAN), Cetafen, Calpol, Dolono, Febrol, Genapap, Genebs, Mapap, Panadol It is an OTC medicine used to relieve mild to moderate pain and fever. Acetaminophen is a p-aminophenol derivative commonly known as Tylenol or Paracetamol.
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